Zoekresultaten - D.M. Margolis

Differential effects of HIV latency-reversing agents on T cell phenotype and function: implications for HIV cure door G. Clutton, N. Archin, Y. Xu, D.M. Margolis, N. Goonetilleke

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Single cell analysis of HIV latency reveals diverse proviral and host cell behaviour door E.P. Browne, T. Bradley, G. Ferrari, B.F. Haynes, D.M. Margolis

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SMAC mimetics are potent latency reversal agents with single agent and combination activity ex vivo door R.M. Dunham, G.C. Sampey, D.M. Irlbeck, E.P. Browne, D.M. Margolis

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SMAC mimetics reverse HIV latency by selective activation of the non-canonical NF-κB pathway door G.C. Sampey, D.M. Irlbeck, D.M. Margolis, R.M. Dunham, E.P. Brownel

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PP 3.11 - 00171 The chromatin insulator CTCF inhibits HIV gene expression door S. Burgos, S. Jefferys, J. Peterson, J. Parker, A. Manickam, J. Simon, D.M Margolis, E.P. Browne

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Sting agonist as a kick and kill agent to target the HIV reservoir door M. Mavigner, A.D. Brooks, A. Koblansky, C. Galardi, H. Madsen, D.M. Margolis, G. Silvestri, A. Chahroudi

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PP 2.9 - 00125 Impact of latency reversal agents on estrogen receptor alpha gene and protein expression door C. Ceriani, K.L. Lemu, A. Abeyta-Lopez, B. Allard, K.S. James, D.M. Margolis, N.M. Archin

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Induction of HIV from latency by a novel molecule door N.M. Archin, D. Boden, J. Kirchherr, B. Allard, K. Sholtis, J.D. Kuruc, G. Kraus, D.M. Margolis

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PP 1.4 - 00037 Histone decrotonylation uniquely regulates HIV-1 transcription and can be modulated to control HIV-1 latency door T.L. Simermeyer, D. Li, L.M. Wong, C. Aquino, Y. Tang, E.P. Browne, N.M. Archin, D.M. Margolis, G. Jiang

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Triazol-1-ol analogues as novel therapeutic leads towards reactivating and eradicating latent HIV-1 by manipulating SUMOylation of STAT5 door A. Bosque, A. Macedo, A. Spivak, C.L. Novis, L.J. Martins, M. Szaniawski, N.M. Archin, P.A. Luciw, D.M. Margolis, V. Planelles

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PP 4.14 - 00173 Antiretroviral therapy repairs CD4 T cell dysregulation in people living with HIV door A. Sponaugle, A.M. Weideman, J. Ranek, N. Archin, D.M. Margolis, B.G. Vincent, N. Stanley, G. Atassi, M.G. Hudgens, J. Eron, N. Goonetilleke, D. Kuritzkes, A. Adimora, A. Andrade

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CD8 depletion plus signaling of the non-canonical NF-kB pathway reverses latency in SIV-infected, ART-suppressed rhesus macaques door M. Mavigner, A.D. Brooks, G.K. Tharp, C. Mattingly, N. Schoof, T.H. Vanderford, S.E. Bosinger, G.C. Sampey, C. Galardi, R.M. Dunham, D.M. Margolis, G. Silvestri, A. Chahroudi

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The impact of vorinostat and AGS-004, a dendritic cell-based immunotherapy, on persistent HIV-1 Infection door C. Gay, J.D. Kuruc, S.D. Falcinelli, J. Warren, J.L. Kirchherr, K. Sholtis, B. Allard, E. Stuelke, A. Gamble, A. Plachco, I. Tcherapanova, J.J. Eron, N. Goonetilleke, M. DeBenedette, C.A. Nicolette, N.M. Archin, D.M. Margolis

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Preclinical development of a bispecific HIV x CD3 DART molecule that redirects T cells to kill HIV envelope (env)-expressing cells door J.L. Nordstrom, C. Nixon, J. Pickeral, C.h.-Y. Kao Lam, L. Liu, H. Li, S. Sharma, S. Gorlatov, F. Chen, K. Sampathkumar, G.D. Tomaras, S.M. Alam, P. Tsai, T. Morgan, P.T. Ho, B.F. Haynes, G. Ferrari, J.A. Sung, D.M. Margolis, J. Victor Garcia, S. Koenig

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OP 1.4 - 00053 Definitive evidence of a persistent HIV reservoir in human brain myeloid cells despite ART door Y. Tang, G. Jiang, M. Porrachia, C. Ignacio, L.M. Wong, D. Zhong, J. Du, B. Cotsakis, S. Maske, E. de la Parra Polina, T.L. Simermeyer, D. Li, B. Woodworth, J. Kirchherr, B. Allard, M. Clohosey, G.D. Whitehill, J.J. Eron, N.M. Archin, S.B. Joseph, K. Bar, A. Chaillon, S. Gianella, D.M. Margolis, G. Jiang

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