Bias, Precision and Timeliness of Historical (Background) Rate Comparison Methods for Vaccine Safety Monitoring: An Empirical Multi-Database Analysis by Xintong Li, Lana YH Lai, Anna Ostropolets, Faaizah Arshad, Eng Hooi Tan, Paula Casajust, Thamir M. Alshammari, Talita Duarte-Salles, Evan P. Minty, Carlos Areia, Nicole Pratt, Patrick B. Ryan, Patrick B. Ryan, George Hripcsak, George Hripcsak, Marc A. Suchard, Marc A. Suchard, Martijn J. Schuemie, Martijn J. Schuemie, Martijn J. Schuemie, Daniel Prieto-Alhambra, Daniel Prieto-Alhambra

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