Nancy Bonini
Nancy M. Bonini (born 1959) is an American
neuroscientist and
geneticist, best known for pioneering the use of
''Drosophila'' as a
model organism to study
neurodegeneration of the human brain. Using the ''Drosophila'' model approach, Bonini's laboratory has identified
genes and
pathways that are important in the development and progression of neurodegenerative diseases such as
Amyotrophic lateral sclerosis (ALS, also called Lou Gehrig's Disease),
Alzheimer's disease, and
Parkinson's disease, as well as aging, neural injury and regeneration, and response to environmental toxins.
A
professor of
biology at the
University of Pennsylvania since 1994, Bonini has held appointments as the inaugural Lucille B. Williams Term Professor of Biology (2006–2012), an Investigator of the
Howard Hughes Medical Institute (2000–2013), and the Florence RC Murray Professor of Biology (since 2012). She was
editor of the ''
Annual Review of Genetics'' from 2018-2021.
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