Search Results - R. Dunham

Protein crotonylation sensitizes SMACm disruption of latent HIV by modulating the ncNF-κB signaling pathway at the step of p100 cleavage into p52 by J. Guochun, D. Li, S. Falcinelli, L. Wong, C. Garrido, C. Galardi, R. Dunham, E. Brown, N. Archin, D. Margolis

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The latency reversal activity of the SMAC mimetic AZD5582 in ART-suppressed SIV-infected rhesus macaques is potentiated by CD8a cell depletion by M. Mavigner, A. Brooks, C. Mattingly, T. Vanderford, B. Keele, J. Lifson, R. Dunham, D. Margolis, G. Silvestri, A. Chahroudi

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Evaluation of IAP/SMAC mimetics as latency reversal agents in primary cells and cytokine induction in in vivo models predictive of cytokine release by B. Howell, W. Shipe, G. Adam, S. Quan, L. Li, C.N.A. Sim, R. Dunham, D. Margolis, B. Henry, D. Hazuda

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Evaluating latency reactivation synergies between the bromodomain inhibitor iBET-151 and the SMAC mimetic AZD5582 in SIV-infected macaques on ART by A.A. Okoye, Y. Fukazawa, B.E. Randall, R. Lum, B. Varco-Merth, S.D. Falcinelli, J. Smedley, R. Dunham, J.D. Lifson, L.J. Picker

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The SMAC mimetic AZD5582 reverses HIV latency as a single agent in resting primary CD4+ T cells by G. Sampey, D. Irlbeck, E. Browne, M. Kanke, E. Cule, S. Wills, S. Falcinelli, Z. Wang, J. Kircherr, B. Allard, E. Stuelke, K. Sholtis, R. Ferris, J. Brehm, D. Favre, J.-P. Routy, C. Jones, N. Archin, D. Margolis, R. Dunham

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