The Gene Ontology Handbook

This book is open access under a CC BY 4.0 license. This book provides a practical and self-contained overview of the Gene Ontology (GO), the leading project to organize biological knowledge on genes and their products across genomic resources. Written for biologists and bioinformaticians, it covers...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Dessimoz, Christophe (Editor), Škunca, Nives (Editor)
Format: Electronic eBook
Language:English
Published: New York, NY : Springer New York : Imprint: Humana, 2017.
Edition:1st ed. 2017.
Series:Methods in Molecular Biology, 1446
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Online Access:Link to Metadata
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Table of Contents:
  • Primer on Ontologies
  • The Gene Ontology and the Meaning of Biological Function
  • Primer on the Gene Ontology
  • Best Practices in Manual Annotation with the Gene Ontology
  • Computational Methods for Annotation Transfers from Sequence
  • Text Mining to Support Gene Ontology Curation and Vice Versa
  • How Does the Scientific Community Contribute to Gene Ontology?
  • Evaluating Computational Gene Ontology Annotations
  • Evaluating Functional Annotations of Enzymes Using the Gene Ontology
  • Community-Based Evaluation of Computational Function Prediction
  • Get GO!: Retrieving GO Data Using AmiGO, QuickGO, API, Files, and Tools
  • Semantic Similarity in the Gene Ontology
  • Gene-Category Analysis
  • Gene Ontology: Pitfalls, Biases, and Remedies
  • Visualizing GO Annotations
  • A Gene Ontology Tutorial in Python
  • Annotation Extensions
  • The Evidence and Conclusion Ontology (ECO): Supporting GO Annotations
  • Complementary Sources of Protein Functional Information: The Far Side of GO
  • Integrating Bio-Ontologies and Controlled Clinical Terminologies: From Base Pairs to Bedside Phenotypes
  • The Vision and Challenges of the Gene Ontology.