Hydrogels in Regenerative Medicine and Other Biomedical Applications

• Other Authors: Jervis, Peter John (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
• Subjects: Technology: general issues; Biotechnology; polyvinyl alcohol; cobalt-substituted hydroxyapatite; diabetic foot ulcers; hydrogels; antibacterial ability; chitosan; cellulose; hydrogel; wound dressings; burn wounds; diabetic wounds; chronic wounds; acute wounds; methacrylate glycol chitosan; beta-cyclodextrin; triclosan; antibacterial; tissue bio-adhesive; poly(2-hydroxyethyl methacrylate); 3D scaffold; RGDS; chronic lymphocytic leukemia; B cell survival; synthetic mimic of heparin; poly(sodium-4-styrenesulfonate); myoblast; myogenic differentiation; fusion; focal adhesion kinase (FAK); supramolecular; dehydrodipeptide; drug delivery; wound healing; cancer; smart materials; peptidomimetic; 3d printing; PLCL; decellularization; angiogenesis; dECM hydrogel; adipose tissue regeneration; entrapment neuropathy; animal model; ultrasound; carpal tunnel syndrome; alginate; PNIPAM-based graft copolymers; thermo-responsive; shear-responsive; LCST adjustment; sol-gel transition; rheological properties; injectability; poly(vinyl alcohol); decellularized cartilage matrix; bioprinting; thiol-ene cross-linking; sodium alginate; betamethasone; cartilage tissue engineering; testicular tissue transplantation; fertility preservation; VEGF; PDGF; vascular maturity; necrosis inhibitor; spermatogonia stem cells; nanoparticles; tissue engineering; functionalization; Chit-HVP; Chit-RGD; XPS; NEXAFS; h-osteoblasts; tunable lens; ultrasonic detection; deep detection; phononic crystal; PVA; marjoram oil; kaolin; hemostatic dressing; antibacterial and antioxidant wound dressing; human hair keratin; fibrinogen; injectable hydrogel; human gingival fibroblast; biomaterials; biocompatibility; in vitro model; hybrid hydrogel; extracellular matrix; microenvironment mimicking matrix; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

Great strides have been made in the area of hydrogel science since the first hydrogels were described in the 1960s. Hydrogels usually consist of three-dimensional matrices of hydrophilic polymers, held together by chemical or physical crosslinks, or supramolecular assemblies of small amphiphilic molecules. The gelation process occurs in response to a physical or chemical stimulus, such as temperature, pH, electric or magnetic field, enzymatic modification, light, and others. Consisting of mainly water molecules, they represent a unique class of materials, with many applications such as cell therapeutics, cartilage/bone regeneration, sustained drug release and drug delivery systems, tissue engineering, and 3D bioprinting. Despite these great strides, there is still much more to discover in this area. This Special Issue is focused on the use of hydrogels in tissue and bone regeneration. Hydrogels are particularly suited for this purpose as their physical characteristics resemble that of the extracellular matrix; as such, they have found applications as an extracellular medium for cancer cells, stem cells, and neuronal cells. This Special Issue also includes research papers on the other biomedical applications of hydrogels.