Synthesis of Heteroaromatic Compounds

• Other Authors: Sloop, Joseph (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
• Subjects: Research & information: general; Chemistry; Organic chemistry; heteroaromatics; C-H bond functionalization; oxidative cyclization; cross-coupling; amination; triazoles; palladium; carbene ligands; heterocycles; nitrogen-containing heterocycles; synthesis; antiviral agents; viruses; COVID-19; inhibition; Mpro inhibitors; drug design and synthesis; structure-activity relationships (SAR); s-tetrazine; 4H-1,2,4-triazole; pinner reaction; 1,2,3-triazole; fused 1,2,3-triazole; 1,2,3-triazolo[4,5-b]pyrazine; 1,2,3-triazolo[4,5-c]pyridazine; 1,2,3-triazolo[4,5-d]pyridazine; 1,2,3-triazolo[1,5-a]pyrazine; 1,2,3-triazolo[1,5-b]pyridazine; triazolopyrazine; triazolopyridazine; practical applications; spiro π-conjugated compound; chiral compound; thiophene; furan; pyrrole; nucleophilic aromatic substitution; circular dichroism; circularly polarized luminescence; pyridines; 1,3,4-thiadiazoles; 1,3-thiazoles; hydrazonoyl halides; molecular docking; anticancer activity; 1,3,4-oxadiazoles; organic ligands; substitution; diisopropyl iminodiacetate; pyrimidine; benzimidazole; aza-Diels-Alder reaction; Povarov reaction; oxidation; fluorescence; aggregation-induced emission; mechanochromic properties; heterocycle; natural product; nicotinic acid; fungicidal activity; 4-pyrone; DMF-DMA; enamination; cycloaddition; merocyanine; 1,6-conjugate addition; solvatochromism; fluorophore; acetylcoumarin; thiazoles; VEGFR-2; polyfluoroflavones; 1H-1,2,4-triazole; imidazole; regioselectivity; azolyl-substituted flavones; photoluminescence; 4-pyridone; oxazinone; ring-opening; aldehyde-lactol tautomerism; ammonium acetate; diazirine; medicinal chemistry; photoaffinity labeling; metathesis; carboaromatics; 4,5-dihydro-5-oxo-pyrazolo[1,5-a]thieno[2,3-c]pyrimidines; novel scaffold; molecular dynamic studies; proximity frequencies (PF); GABAA receptor subtype; GABAA receptor ligands; antibacterial; anticancer; antifibrotic; antifungal; antimicrobial; antiviral; appel salt; 1,2,3-dithiazole; disulfide bridge; herbicidal; chalcone; heteroaromatic; hybrid chalcone; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

This Special Issue, entitled the "Synthesis of Heteroaromatic Compounds", is an outstanding collection of fourteen original research papers and six review articles that discuss the advances made in both conventional and green preparatory methods, as well as the properties and applications of heteroaromatic molecules in industrial and medicinal chemistry areas of study.The collected works featured herein collate contributions from a truly international and diverse array of ninety experts in the fields of heteroaromatic compound synthesis, QSAR studies, computational chemistry and molecular docking, as well as bioactivity studies.