Research of Pathogenesis and Novel Therapeutics in Arthritis 2.0

• Andre forfattere: Tang, Chih-Hsin (Editor)
• Format: Electronisk Book Chapter
• Sprog: engelsk
• Udgivet: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
• Fag: Medicine; Pharmacology; rheumatoid arthritis; exercise therapy; autoimmune disorder; treadmill running; exercise; articular cartilage; collagen-induced arthritis; pro-inflammatory cytokine; connexin 43; osteoporosis; microenvironment; inflammation; mesenchymal stem/stromal cells; bone injury; repair/regeneration; microparticles; joint inflammatory diseases; Wnt signaling; Dkk-1; biologics; ankylosing spondylitis; axial spondyloarthritis; bone homeostasis; osteoarthritis; aging; PTOA; gene expression; RNA-seq; cartilage degeneration; scRNA-seq; chondrocytes; animal model; pain; melatonin; angiotensin II; arthritis; bone erosion; tumor necrosis factor; renin-angiotensin system; angiotensin II type 1 receptor; psoriatic arthritis; osteoclastogenesis; miR-941; WNT16; polymorphism; genetic predisposition; mutation; methotrexate; interleukin; targeted therapy; interstitial lung disease; subclinical involvement; ACPA; pulmonary function testing; CPET; surfactant protein D; DLCO; HRCT; lymph node stromal cells; tolerance; autoimmunity; citrullination; macrophages; PADI2; inflammatory cytokines; adhesion; apoptosis; L5; macrophage foam cell; CD11c expression; atherosclerosis; rheumatoid arthritis (RA); synovium; cytokines; HHV-7; PCR; ELISA; immunohistochemistry; adipocyte; infrapatellar fat pad; anterior cruciate ligament; cartilage; whole transcriptome sequencing; biomarker; CRISPR/Cas9; miRNA; genome editing; autoimmune arthritis; Nkx2-3; B cell activation; Spondyloarthritis; ankylosing arthritis; interleukin-17; interleukin-23; tibial compression; gut microbiome; antibiotics; LPS; adults; juvenile; immune; laser blood irradiation; low-level laser; systemic; naïve rheumatoid arthritis; CD4+ T-lymphocytes; methotrexate response; IFNγ, IL-17A; STAT expression; osteonecrosis; taurine; mitochondrial function; glucocorticoid; discoidin domain receptors 1 (Ddr1); osteoarthritis (OA); autophagy; terminal differentiation; Treg; Th17; microRNA; transcriptional factor; JAK/STAT; Janus kinase inhibitors; cardiovascular system; heart failure; thromboembolic; lipid profile disturbances; treatment; molecular mechanisms; biomarkers; prevention; collagen triple helix repeat containing 1; CTHRC1; cartilage destruction; fibroblast-like synoviocytes
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Arthritis has a high prevalence globally and includes over 100 types, the most common of which are rheumatoid arthritis, osteoarthritis, psoriatic arthritis, and inflammatory arthritis. All types of arthritis share common features of the disease, including monocyte infiltration, inflammation, synovi...