Transcriptional Regulation and Its Misregulation in Human Diseases

• Other Authors: Casamassimi, Amelia (Editor), Ciccodicola, Alfredo (Editor), Rienzo, Monica (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
• Subjects: Research & information: general; Biology, life sciences; parallel reporter assay; rs684232; FOXA1; VPS53; FAM57A; GEMIN4; metabolically healthy obesity; epigenetic biomarkers; metabolic syndrome; DNA methylation; adult-onset asthma; building dampness and molds; endotypes; environmental intolerance; transcriptomics; pathobiological mechanisms; SNAI1; metastasis; post-translational modifications; epigenetic; EMT; FOXP3; ATF3; post-translational modification; transcriptional activity; HOX-code; NKL-code; TALE-code; TBX-code; chimeric RNAs; Fusion RNAs encoding protein; fusion transcript; linc-223; miR-223 host gene; trans-splicing; alternative splicing; CCL1; myeloid cell differentiation; C-type lectin; chronic myeloid leukemia; anthrax; Bacillus anthracis; 16S rRNA; detection; identification; real-time PCR; RT-PCR; NRF3; protein homeostasis; lipid homeostasis; proteasome; translation; GGPP; macropinocytosis; cancer; obesity; brown adipose tissue; transcriptome; cold exposure; aging; HCC-specific small functional protein; NONHSAT013026.2/Linc013026-68AA; fine tuner of cancer formation; dark proteome; hepatocellular carcinoma; hair cells; adult cochlea; regeneration; transcription factor; bioinformatics; cheA; flhDC; GlmY; Proteus mirabilis; QseEF; rcsB; swarming; HIF-1α; YY1; ALL; XDP; retrotransposon; SVA; splicing; epigenetics; transcription; homeodomain; PBX1; mRNA export; TREX; TREX-2; NPC; lifespan; neurodegenerative diseases; endogenous retroviruses (ERVs); transcriptional regulation; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

Transcriptional regulation is a critical biological process that allows the cell or an organism to respond to a variety of intra- and extracellular signals, to define cell identity during development, to maintain it throughout its lifetime, and to coordinate cellular activity. This control involves...