The Role of Toll-Like Receptors (TLR) in Infection and Inflammation

• Other Authors: Kircheis, Ralf (Editor), Planz, Oliver (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
• Subjects: Medicine; hepatitis C virus; infection; innate immunity; Toll-like receptor; cytokines; Omicron; spike protein; SARS-CoV-2; COVID-19; cytokine storm; NF-kappaB; Toll-like receptor (TLR); monoclonal antibody TLR4; compression force; MAPKs; AKT; human PDL; sterile inflammation; TLR; immune system; inflammation; antiviral; polymorphism; sepsis; septic shock; TLR7; TLR8; 2'-O-ribose-methylation; RNase T2; immune activation; CD14; LPS; hop; TLR4; oligonucleotide; sncRNA; endocytosis; broad-spectrum; antiviral agent; nucleolin; virus entry; immunoregulation; RNA therapeutics; TLR7 (Toll-like receptor 7); MUC1 (Mucin 1); aluminum adjuvant; tumor vaccine; immunotherapy; toll-like receptor-2 (TLR2); advanced glycation end products (AGEs); aquaporin-3 (AQP3); histone deacetylase inhibitor; diabetes; keratinocytes; skin; n/a; TLR4-RAGE crosstalk; glucose; lipopolysaccharide (LPS); inflammatory; alveolar macrophages
• Online Access: DOAB: download the publication; DOAB: description of the publication

Toll-like receptors (TLRs) represent a powerful system for the recognition and elimination of pathogen-associated molecular patterns (PAMPs) from bacteria, viruses, and other pathogens and damage-associated molecular patterns (DAMPs) released from dying cells. Typical PAMPs include bacterial cell wa...