Marine Natural Products as Anticancer Agents 2.0

Global cancer incidence and death are expected to increase in the next decades. Inappropriate therapeutic regimens and tumor recurrence due to the development of drug resistance are two major clinical challenges impacting poor patient outcomes, which is critical to the discovery and development of n...

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Other Authors: Alves, Celso (Editor), Diederich, Marc (Editor)
Format: Electronic Book Chapter
Language:English
Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
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DOAB: description of the publication
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520 |a Global cancer incidence and death are expected to increase in the next decades. Inappropriate therapeutic regimens and tumor recurrence due to the development of drug resistance are two major clinical challenges impacting poor patient outcomes, which is critical to the discovery and development of new anticancer drugs. Over the last few decades, the marine environment has proved to be a key source of molecules with potent anticancer properties. The Special Issue, "Marine Natural Products as Anticancer Agents 2.0", gathered eleven publications, including two reviews and nine research articles, about the anticancer activities of marine natural and/or derived products on in vitro 2D and 3D cellular models, and/or in vivo models of colorectal, breast, lung, myeloma, liver, leukemia, and melanoma cancers. Altogether, the eleven scientific papers published in this Special Issue provide an exciting overview of marine natural products as potential anticancer agents. 
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653 |a Clavatadine C 
653 |a spirocyclic bromotyrosines 
653 |a cytotoxicity 
653 |a cancer selectivity 
653 |a marine compounds 
653 |a melanoma A-375 cell line 
653 |a Sarcophyton convolutum 
653 |a sarcoconvolutum A-E 
653 |a cembrenoids 
653 |a anti-angiogenesis 
653 |a bromophenols 
653 |a tube formation 
653 |a vasculogenic mimicry 
653 |a brefeldin A 
653 |a ester derivative 
653 |a chronic myelogenous leukemia 
653 |a BCR-ABL 
653 |a proliferation inhibition 
653 |a molecular modeling 
653 |a 5-O-(N-Boc-l-alanine)-renieramycin T 
653 |a Xestospongia sp. 
653 |a marine sponge 
653 |a lung cancer 
653 |a anti-cancer 
653 |a cancer stem cells 
653 |a apoptosis 
653 |a Akt 
653 |a c-Myc 
653 |a migrastatics 
653 |a cell migration 
653 |a cell invasion 
653 |a metastasis 
653 |a terpenes 
653 |a algae 
653 |a marine natural products 
653 |a mitochondrial dysfunction 
653 |a oxidative stress 
653 |a anticancer 
653 |a Sphaerococcus coronopifolius 
653 |a seaweed 
653 |a Laminaria japonica 
653 |a Laminaria japonica peptides 
653 |a cancer 
653 |a liver 
653 |a cell cycle 
653 |a porphyrin 
653 |a Isabela 
653 |a hemin 
653 |a X-ray diffraction 
653 |a NOESY NMR 
653 |a cytotoxic 
653 |a colorectal cancer 
653 |a 5-fluorouracil 
653 |a 7S,15R-dihydroxy-16S,17S-epoxy-docosapentaenoic acid 
653 |a tumor-associated macrophages 
653 |a chemoresistance 
653 |a fucoidan 
653 |a immunopotentiation 
653 |a immunomodulatory 
653 |a immunotherapy 
653 |a cancer treatment 
653 |a cytokines 
653 |a n/a 
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