Marine Natural Products as Anticancer Agents 2.0

• Other Authors: Alves, Celso (Editor), Diederich, Marc (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
• Subjects: Medicine; Pharmacology; Clavatadine C; spirocyclic bromotyrosines; cytotoxicity; cancer selectivity; marine compounds; melanoma A-375 cell line; Sarcophyton convolutum; sarcoconvolutum A-E; cembrenoids; anti-angiogenesis; bromophenols; tube formation; vasculogenic mimicry; brefeldin A; ester derivative; chronic myelogenous leukemia; BCR-ABL; proliferation inhibition; molecular modeling; 5-O-(N-Boc-l-alanine)-renieramycin T; Xestospongia sp.; marine sponge; lung cancer; anti-cancer; cancer stem cells; apoptosis; Akt; c-Myc; migrastatics; cell migration; cell invasion; metastasis; terpenes; algae; marine natural products; mitochondrial dysfunction; oxidative stress; anticancer; Sphaerococcus coronopifolius; seaweed; Laminaria japonica; Laminaria japonica peptides; cancer; liver; cell cycle; porphyrin; Isabela; hemin; X-ray diffraction; NOESY NMR; cytotoxic; colorectal cancer; 5-fluorouracil; 7S,15R-dihydroxy-16S,17S-epoxy-docosapentaenoic acid; tumor-associated macrophages; chemoresistance; fucoidan; immunopotentiation; immunomodulatory; immunotherapy; cancer treatment; cytokines; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

Global cancer incidence and death are expected to increase in the next decades. Inappropriate therapeutic regimens and tumor recurrence due to the development of drug resistance are two major clinical challenges impacting poor patient outcomes, which is critical to the discovery and development of n...