The Ins and Outs of miRNAs as Biomarkers

• Andere auteurs: Iacomino, Giuseppe (Redacteur), Lauria, Fabio (Redacteur)
• Formaat: Elektronisch Hoofdstuk
• Taal: Engels
• Gepubliceerd in: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
• Onderwerpen: Research & information: general; Biology, life sciences; mi-RNA; physical exercise; gene expression; stress; head and neck cancer; miRNA; chemoresistance; protocol; systematic review; hazard ratio; patient survival; up-regulation; down-regulation; microRNA; circulating miRNA; theranostic biomarkers; chemosensitivity; melanoma; meta-analysis; miRNAs; microRNAs; liver neoplasms; angiogenesis; cancer biomarkers; transfection; qRT-PCR; plasma; amplification efficiency; EBV; LMP1; nasopharyngeal cells; expression profiling; chronic low-grade inflammation; inflammation-associated biomarkers; overweight and obesity; children/adolescents; sex-related associations; DNA copy number variation; comparative study; progenitor cells; amniotic fluid; leiomyoma; myometrium; divergent cell commitment; linear dysregulation; circulating microRNAs; extracellular miRNA; nasopharyngeal carcinoma; miRNA-based diagnosis; HNSCC; tumor-suppressor; miR-30e-5p; FOXD1; TCGA; cervical cancer; non-coding RNAs; diagnosis; prognosis; therapeutics; regulation of gene expression; alveolar epithelial type II cells; type II pneumocytes; ATII; AECII; flow cytometry; autofluorescence; pathway analysis; TGF-beta; homeostasis; EMT; RNA-based therapeutic; personalized medicine; translational medicine; breast cancer; diagnostics; therapy response; hepatitis C virus; liver injury; microRNA-192; microRNA-29a; HCV genotype-3
• Online toegang: DOAB: download the publication; DOAB: description of the publication

miRNAs are small noncoding RNAs that control gene expression at the post-transcriptional level. It has been recognized that dysregulation of miRNAs reflects the state and function of cells and tissues, contributing to their dysfunction. The identification of hundreds of extracellular miRNAs in biolo...