Heme Oxygenase (HO)-1 as an Immunoregulator in Health and Disease

• Andere auteurs: Lianos, Elias (Redacteur), Detsika, Maria G. (Redacteur)
• Formaat: Elektronisch Hoofdstuk
• Taal: Engels
• Gepubliceerd in: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
• Onderwerpen: Medicine; heme oxygenase 1; immune response; inflammation; immune-mediated injury; &nbsp
• Online toegang: DOAB: download the publication; DOAB: description of the publication

Heme oxygenase (HO)-1 is a well-known, cytoprotective enzyme, responsible for the enzymatic conversion of heme into the anti-apoptotic and antioxidant by-products, biliverdin, bilirubin and carbon monoxide. However, HO-1 also regulates responses via mechanisms that are independent of the generation...