Epilepsy Seizures without Triggers

According to the World Health Organization, nearly 80% of people with epilepsy live in low- and middle-income countries and could live seizure-free if properly diagnosed and treated. Among the structural and genetic triggers that may lead to epilepsy are head trauma, abnormal synaptic connectivity,...

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Opis bibliograficzny
Kolejni autorzy: Fatima Shad, Kaneez (Redaktor)
Format: Elektroniczne Rozdział
Język:angielski
Wydane: IntechOpen 2023
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Opis
Streszczenie:According to the World Health Organization, nearly 80% of people with epilepsy live in low- and middle-income countries and could live seizure-free if properly diagnosed and treated. Among the structural and genetic triggers that may lead to epilepsy are head trauma, abnormal synaptic connectivity, receptor subunits anomalies, and atypical ionic channel function. Developing brains are specifically susceptible to seizures for many reasons, for example, the presence of enhanced excitation due to the early production of excitatory neurotransmitters, and the fact that the inhibitory neurotransmitter GABA causes excitation early in life. These studies help to clarify why the very young brain is exceptionally prone to seizures. The chapters presented in this book describe how structural, genetic, infectious, and metabolic abnormalities can lead to epileptogenesis. Nevertheless, many underlying disease mechanisms that can lead to epilepsy remain unknown.
Opis fizyczny:1 electronic resource (118 p.)
ISBN:intechopen.100833
9781803566009
9781803565996
9781803566016
Ograniczenie dostępu:Open Access