Clinical Relevance of Brain Atrophy Measures in Multiple Sclerosis

Magnetic resonance imaging of the brain and spinal cord in patients with multiple sclerosis is crucial for diagnosis as well as monitoring and predicting disease activity. Comprehensive MR measurements including assessment of brain and spinal cord volume changes have the potential to improve patient...

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Main Author: Uher, Tomáš (auth)
Format: Electronic Book Chapter
Language:English
Published: Prague Karolinum Press 2023
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520 |a Magnetic resonance imaging of the brain and spinal cord in patients with multiple sclerosis is crucial for diagnosis as well as monitoring and predicting disease activity. Comprehensive MR measurements including assessment of brain and spinal cord volume changes have the potential to improve patient monitoring, allow earlier detection of subclinical disease activity, and identify patients with depleted brain reserve who are at highest risk of disability progression. Cerebral atrophy measurements are now a secondary outcome of many clinical trials, although their wider use in routine clinical practice is still hampered by some technical limitations. However, evidence from clinical practice shows that assessment of brain and spinal cord volume change is feasible and has the potential to improve patient treatment. 
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650 7 |a Medicine  |2 bicssc 
653 |a multiple sclerosis 
653 |a brain atrophy 
653 |a diagnosis 
653 |a measurements 
653 |a disease 
653 |a monitoring 
653 |a magnetic resonance 
653 |a cerebral atrophy 
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