Separation, Extraction and Purification of Natural Products from Plants

• Other Authors: Gong, Xingchu (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
• Subjects: Research & information: general; Chemistry; Analytical chemistry; azide; cilostazol; COVID-19; genotoxic impurity; validation; LLE; ethanol precipitation; loss of active ingredients; mixing condition indicator; micromesh mixer; Caulis sinomenii; microfiltration; ultrafiltration; sinomenine hydrochloride; separation and purification; Phyllanthus urinaria L.; ellagic acid; mechanochemical-assisted extraction; macroporous adsorption resin; compositional monosaccharides; HPLC-ELSD/PDA combined with HPSEC-MALLS-RID; molecular weight; quality markers (Q-marker); red ginseng polysaccharides; Xiaochaihu (XCH) formula; preparations; quality control; standard; 4-aryl-3,4-dihydropyrimidin-2(1H)-ones; teicoplanin aglycone; chiral HPLC; enantioselectivity; molecular docking; molecular dynamics; Radix Angelicae sinensis; volatile oil; Box-Behnken design; steam distillation; extraction kinetics; design space; dill; Anethum graveolens L.; essential oil; Neofusicoccum parvum; antifungal mechanism; near-infrared spectroscopy; Astragali radix; alcohol precipitation; accuracy profile; Vis-NIR spectroscopy; Ginkgo biloba L. leaves; in-line analysis; column chromatographic elution; consistency evaluation; multivariate statistical process control (MSPC); quality by design; Xiaochaihu capsule; quantitative chromatographic fingerprint; definitive screening design; Plackett-Burman; Forsythia suspensa; Lonicera japonica
• Online Access: DOAB: download the publication; DOAB: description of the publication

This special issue "Separation, Extraction and Purification of Natural Products from Plants" contains high-quality multidisciplinary research and review articles on various aspects of natural products. Quality by design (QbD) is a science-based and risk-based concept. The implementation of QbD ensures consistent high quality of natural product. The advantages of the concept are reflected in the researches collected in this special issue, such as the two articles on the optimization of the steam distillation process from Jiangxi University of Chinese Medicine. Process analytical technology (PAT) is an important part of the implementation of QbD concept. Two articles from Dr. Li Wenlong combines spectroscopy and chemometrics, providing good examples on the monitoring of natural product preparation process. Chromatographic separation and analysis are very important for quality control of natural products. There are six articles from different countries focusing on this topic. There are two articles investigating separation technologies, including membrane filtration and ethanol precipitation. Traditional Chinese medicines are also an important category of natural products. A review from Zhejiang University talks about the quality control of Xiaochaihu Capsule. I received a lot of help from friends from universities and enterprises in completing this special issue. I would like to express my gratitude to them. My thanks also go to the editors of this journal of Separations.