Diagnosis of Lower Genital Tract Disease

• Other Authors: Bottari, Fabio (Editor), Iacobone, Anna Daniela (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
• Subjects: Medicine; genitourinary syndrome of menopause (GSM); vaginal dryness; vaginal atrophy; vaginal health index (VHI); estrogen; vaginal maturation index (VMI); fractional CO2 laser; human papillomavirus; HPV; bladder cancer; HPV detection; urothelial carcinoma; transitional cell carcinoma; cervical intraepithelial neoplasia; follow-up; real time PCR; genotyping; concordance; vaginosonography; transvaginal ultrasound; cervical cancer; MRI and gynecological oncology diagnosis; atypical endometrial hyperplasia; endometrial cancer; hysteroscopy; self-collection; vaginal self-sample; first-void urine; cervical cancer screening; diagnostic accuracy; HPV 16 sub-lineages; anal cancer; high-grade vaginal intraepithelial neoplasia (VAIN); smoking; previous hysterectomy for CIN2+; colposcopic grade; papillary lesion; vascular pattern; vulvar extramammary Paget's disease (EMPD); cervico-vaginal involvement; atypical glandular cytology; colposcopic-guided biopsy; Paget cells; E6; E7; cervical intraepithelial lesion; biomarker; Serbia; colposcopy; QC; QA; colposcopy sensitivity; cervical cancer prevention; CIN; SIL; colposcopy standards; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

Lower genital tract diseases include vulvovaginal and HPV-related diseases, ranging from benign to pre-neoplastic and neoplastic lesions. Nowadays, there has been increasing interest in innovative methods to diagnose and prevent cervical cancer through HPV primary screening programs. However, other lower genital tract diseases are unrelated to HPV infection; hence, cytology, colposcopy, and sonography might play a crucial role in assessment and management. This Special Issue aims to address current and emerging issues in the field of the diagnosis, assessment, staging, and management of HPV-related and not-related pathology of the lower female anogenital tract. These may include new advancements in HPV testing and laboratory biomarkers, investigations on the actual role of cytology and implementation of diagnostic tools to implement differential diagnosis, and the current clinical management of lower genital tract diseases.