The Transcription Factor Nrf2
Due to that at present, the majority of diseases are associated with alterations in oxidative stress and inflammatory processes, and in that Nrf-2 is a modulator of these processes; knowing how this transcriptional factor functions and is regulated opens a therapeutic window to diverse diseases. The...
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| Other Authors: | , , |
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| Format: | Electronic Book Chapter |
| Language: | English |
| Published: |
IntechOpen
2016
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| Subjects: | |
| Online Access: | DOAB: download the publication DOAB: description of the publication |
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| 100 | 1 | |a Antonio Morales-Gonzalez, Jose |4 edt | |
| 700 | 1 | |a Morales-Gonzalez, Angel |4 edt | |
| 700 | 1 | |a Osiris Madrigal-Santillan, Eduardo |4 edt | |
| 700 | 1 | |a Antonio Morales-Gonzalez, Jose |4 oth | |
| 700 | 1 | |a Morales-Gonzalez, Angel |4 oth | |
| 700 | 1 | |a Osiris Madrigal-Santillan, Eduardo |4 oth | |
| 245 | 1 | 0 | |a The Transcription Factor Nrf2 |
| 260 | |b IntechOpen |c 2016 | ||
| 300 | |a 1 electronic resource (210 p.) | ||
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| 520 | |a Due to that at present, the majority of diseases are associated with alterations in oxidative stress and inflammatory processes, and in that Nrf-2 is a modulator of these processes; knowing how this transcriptional factor functions and is regulated opens a therapeutic window to diverse diseases. Therefore, the efforts of various investigation groups are centered on finding activators and/or inhibitors of Nrf-2 to prevent or control diverse diseases, for example, cancer, where it would be important to regulate Nrf-2 in order for it to activate apoptosis pathways in cancerogenous cells, or in neurodegenerative diseases where cell death is predominant, it would be important for Nrf-2 to activate antiapoptotic pathways. | ||
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| 546 | |a English | ||
| 650 | 7 | |a Molecular biology |2 bicssc | |
| 653 | |a Proteins | ||
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| 856 | 4 | 0 | |a www.oapen.org |u https://directory.doabooks.org/handle/20.500.12854/129317 |7 0 |z DOAB: description of the publication |