Muscle Cell and Tissue Novel Molecular Targets and Current Advances

The loss of skeletal muscle mass and strength substantially impairs physical performance and quality of life. This book details some approaches to the treatment of muscle wasting. It also reviews novel applications against pulmonary arterial hypertension such as cell reprogramming and the use of ant...

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Bibliographic Details
Other Authors: Sakuma, Kunihiro (Editor)
Format: Electronic Book Chapter
Language:English
Published: IntechOpen 2021
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Online Access:DOAB: download the publication
DOAB: description of the publication
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520 |a The loss of skeletal muscle mass and strength substantially impairs physical performance and quality of life. This book details some approaches to the treatment of muscle wasting. It also reviews novel applications against pulmonary arterial hypertension such as cell reprogramming and the use of anticancer drugs that induce programmed cell death. Vascular smooth muscle cells (VSMCs) are the most prevalent cell types in blood vessels and serve critical regulatory roles. This publication also introduces mathematical models concerning the molecular mechanism and targets of cyclic guanosine 3',5'-monophosphate (cGMP) in the contraction of VSMCs. This book will be of interest to professionals in clinical practice, medical and health care students, and researchers working in muscle-related fields of science. 
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653 |a pulmonary hypertension, heart failure, apoptosis, aging, autophagy, anatomy 
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