Die Generierung von künstlichen Keimzellen Medizinische, rechtliche und ethische Aspekte
So far, it has not been possible to generate human sperm and egg cells from pluripotent stem cells. However, completion of in vitro gametogenesis (IVG) is expected in the near future because progenitor cells from human gamete have already been generated. Gametes produced this way could fundamentally...
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| Other Authors: | , , , , , |
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| Format: | Electronic Book Chapter |
| Published: |
Baden-Baden
Nomos Verlagsgesellschaft mbH & Co. KG
2023
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| Series: | Ethik in den Biowissenschaften
25 |
| Subjects: | |
| Online Access: | DOAB: download the publication DOAB: description of the publication |
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| 100 | 1 | |a Mall, Eva |4 edt | |
| 700 | 1 | |a Schlatt, Stefan |4 edt | |
| 700 | 1 | |a Gassner, Ulrich M. |4 edt | |
| 700 | 1 | |a Spranger, Tade Matthias |4 edt | |
| 700 | 1 | |a Ranisch, Robert |4 edt | |
| 700 | 1 | |a Rolfes, Vasilija |4 edt | |
| 700 | 1 | |a Mall, Eva |4 oth | |
| 700 | 1 | |a Schlatt, Stefan |4 oth | |
| 700 | 1 | |a Gassner, Ulrich M. |4 oth | |
| 700 | 1 | |a Spranger, Tade Matthias |4 oth | |
| 700 | 1 | |a Ranisch, Robert |4 oth | |
| 700 | 1 | |a Rolfes, Vasilija |4 oth | |
| 245 | 1 | 0 | |a Die Generierung von künstlichen Keimzellen |b Medizinische, rechtliche und ethische Aspekte |
| 260 | |a Baden-Baden |b Nomos Verlagsgesellschaft mbH & Co. KG |c 2023 | ||
| 300 | |a 1 electronic resource (138 p.) | ||
| 336 | |a text |b txt |2 rdacontent | ||
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| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 1 | |a Ethik in den Biowissenschaften |v 25 | |
| 506 | 0 | |a Open Access |2 star |f Unrestricted online access | |
| 520 | |a So far, it has not been possible to generate human sperm and egg cells from pluripotent stem cells. However, completion of in vitro gametogenesis (IVG) is expected in the near future because progenitor cells from human gamete have already been generated. Gametes produced this way could fundamentally expand both the understanding of early human development and reproductive treatments for infertility. This expert report provides basic medical information on the development of human gametes, considers relevant legal standards and key ethical issues such as balancing genetic parenthood against potential harms resulting from IVG. With contributions by Ulrich M. Gassner | Eva Mall | Stefan Schlatt | Tade Matthias Spranger | Robert Ranisch | Vasilija Rolfes | ||
| 520 | |a Bisher ist es noch nicht gelungen, menschliche Ei- und Samenzellen aus pluripotenten Stammzellen zu gewinnen. Der Abschluss einer In-vitro-Gametogenese (IVG) wird jedoch in naher Zukunft erwartet, da bereits Vorläuferzellen von humanen Gameten erzeugt werden konnten. Auf diese Weise generierte Keimzellen könnten ebenso das Verständnis der frühen menschlichen Entwicklung wie auch reproduktionsmedizinische Behandlungen von Infertilität grundlegend erweitern. Dieser Sachstandsbericht stellt wesentliche medizinischen Abläufe der Entwicklung menschlicher Gameten dar, betrachtet einschlägige rechtliche Normen und zentrale ethische Aspekte, wie etwa die Abwägung genetischer Elternschaft mit möglichen Schäden infolge einer IVG. Mit Beiträgen von Ulrich M. Gassner | Eva Mall | Stefan Schlatt | Tade Matthias Spranger | Robert Ranisch | Vasilija Rolfes | ||
| 540 | |a Creative Commons |f https://creativecommons.org/licenses/by/4.0/ |2 cc |4 https://creativecommons.org/licenses/by/4.0/ | ||
| 546 | |a German | ||
| 650 | 7 | |a JFMG |2 bicssc | |
| 653 | |a artificial gametes | ||
| 653 | |a gamete progenitor cells | ||
| 653 | |a genetic parenthood | ||
| 653 | |a reproductive medicine | ||
| 653 | |a pluripotent stem cells | ||
| 856 | 4 | 0 | |a www.oapen.org |u https://doi.org/10.5771/9783495993958 |7 0 |z DOAB: download the publication |
| 856 | 4 | 0 | |a www.oapen.org |u https://directory.doabooks.org/handle/20.500.12854/131625 |7 0 |z DOAB: description of the publication |