30 years old: O-GlcNAc Reaches Age of Reason - Regulation of Cell Signaling and Metabolism by O-GlcNAcylation

• Main Author: Tarik Issad (auth)
• Other Authors: Tony Lefebvre (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2015
• Series: Frontiers Research Topics
• Subjects: nutrition; Hexosamine biosynthetic pathway; O GlcNAcylation; OGA; Inflammation; Metabolism; OGT; Cell signaling; epigenetics; Cancer
• Online Access: DOAB: download the publication; DOAB: description of the publication

Hundreds post-translational modifications (PTM) were characterized among which a large variety of glycosylations including O-GlcNAcylation. Since its discovery, O-GlcNAcylation has emerged as an unavoidable PTM widespread in the living beings including animal and plant cells, protists, bacteria and...