Advances in Mucoadhesive Polymers and Formulations for Transmucosal Drug Delivery

• Main Author: Khutoryanskiy, Vitaliy (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: MDPI - Multidisciplinary Digital Publishing Institute 2020
• Subjects: Medicine; chitosan; maltodextrin; Caco-2 cells; alkyl lactate; mucosal drug delivery; thermogelling polymers; buccal mucosa drug delivery; drug delivery; triple co-culture model; oral lichen planus; mucoadhesive polymers; cyclodextrins; paediatric; mucoadhesion; nanoparticles; pectin; furosemide; oral lyophilisates; films; wound healing; pluronic f127; interpolymer complexes; transmucosal permeations; Alzheimer's disease; biocompatibility; poly (vinylpyrrolidone); mucosal membranes; scanning electron microscopic images; pioglitazone; hydrogel; resuspendibility; thermoresponsive polymers; mucoadhesive microspheres; trimethyl chitosan; Candida albicans; xanthan gum; omeprazole; texture profile analysis; acrylated chitosan; mucoadhesive; clotrimazole; clobetasol; Carbopol®; hydroxypropyl cellulose; electrospinning; chitosan derivatives; in vitro permeability; l-arginine; resveratrol; cytotoxicity; retention; thiolated hyaluronic acid; Carbopol; mucoadhesive polymer; rheology; Eudragit® E PO; detachment force; chitosan-catechol; controlled release; PLGA-PEG; liposphere; gellan gum; storage and loss moduli; thiolated chitosan; interpolyelectrolyte complex; poly(2-ethyl-2-oxazoline)
• Online Access: DOAB: download the publication; DOAB: description of the publication

Mucoadhesive polymers are widely used in the design of dosage forms for transmucosal drug delivery to the eye, respiratory, gastrointestinal and reproductive tracts. These routes of drug administration offer a number of advantages including improved drug bioavailability, reduced frequency of adminis...