Application of Antigen Cross-Presentation Research into Patient Care

• Main Author: Marianne Boes (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2017
• Series: Frontiers Research Topics
• Subjects: Medicine; clinical translation; cross-presentation; Vaccination; Immunotherapy; dendritic cell
• Online Access: DOAB: download the publication; DOAB: description of the publication

The activation of adaptive immune responses requires the processing and presentation of protein antigens to lymphocytes. Especially dendritic cells are effective at display of antigen-derived peptides in the form of immunogenic peptide/MHC complexes to CD4 and CD8-positive T cells, and can stimulate...