ATP-gated P2X receptors in Health and Disease

• Main Author: Geoffrey Burnstock (auth)
• Other Authors: Rashid Giniatullin (auth), Andrea Nistri (auth), Baljit S. Khakh (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2015
• Series: Frontiers Research Topics
• Subjects: Neurosciences; Central Nervous System; Ion Channels; neurotransmitters; P2X receptor; ATP
• Online Access: DOAB: download the publication; DOAB: description of the publication

Extracellular ATP is currently recognized as one of the most widely distributed neurotransmitters and neuromodulators in the peripheral and central nervous system. ATP-gated P2X receptors are expressed by neurons, glial and many other non-neuronal cells and represent an attractive target for therape...