Bad Bugs in the XXIst Century: Resistance Mediated by Multi-Drug Efflux Pumps in Gram-Negative Bacteria

• मुख्य लेखक: Hiroshi Nikaido (auth)
• अन्य लेखक: Attilio Vittorio Vargiu (auth), Klaas Martinus Pos (auth), Keith Poole (auth)
• स्वरूप: इलेक्ट्रोनिक पुस्तक अध्याय
• भाषा: अंग्रेज़ी
• प्रकाशित: Frontiers Media SA 2016
• श्रृंखला: Frontiers Research Topics
• विषय: Microbiology (non-medical); Resistance-Nodulation Division transporters; multi-drug-resistant pathogens; antibiotic resistance; Gram-Negative Bacteria; bacterial resistance mechanisms; Superbugs; efflux pumps
• ऑनलाइन पहुंच: DOAB: download the publication; DOAB: description of the publication

The discovery of antibiotics represented a key milestone in the history of medicine. However, with the rise of these life-saving drugs came the awareness that bacteria deploy defence mechanisms to resist these antibiotics, and they are good at it. Today, we appear at a crossroads between discovery o...