Biomedical Insights that Inform the Diagnosis of ME/CFS

• Main Author: Lidbury, Brett (auth)
• Other Authors: Fisher, Paul (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: MDPI - Multidisciplinary Digital Publishing Institute 2020
• Subjects: Medicine; fatigue syndrome; n/a; work rehabilitation; tryptophan metabolism; substrate inhibition; myalgic encephalomyelitis; 3-dioxygenase; ME (Myalgic Encephalomyelitis); assessment; myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS); muscles; hypoacetylation; circadian rhythm; immune system; chronic; CFS (Chronic Fatigue Syndrome); energy metabolism; ME/CFS; immunological; cytokine; bistability; diagnosis; biomarker; symptoms; kynurenine pathway; inflammation and immunity; metabolism; neuro-inflammation; pathology; signaling; exercise; Epstein Barr virus; methylhistidine; hypothalamic-pituitary-adrenal axis; potential biomarkers; critical point; inflammation; histone deacetylation; participatory research; neurology; neuroimmune; activin; mitochondria; patient-driven questionnaire; medical retirement; machine learning; prognosis; gut microbiota; post-exertional malaise; chronic fatigue syndrome; mathematical model; reference intervals; diagnostic biomarker; indoleamine-2
• Online Access: DOAB: download the publication; DOAB: description of the publication

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a severe chronic health condition that is often misunderstood or ignored by health establishments. The lack of definitive diagnostic markers to separate ME/CFS patients from the healthy population as well as from other chronic disorders...