Ca2+ Signaling and Heart Rhythm

• Autore principale: Christopher L.-H. Huang (auth)
• Altri autori: Yunbo Ke (auth), R. John Solaro (auth), Ming Lei (auth)
• Natura: Elettronico Capitolo di libro
• Lingua: inglese
• Pubblicazione: Frontiers Media SA 2016
• Serie: Frontiers Research Topics
• Soggetti: Physiology; Heart; Pak1; SA node; STIM1; TRPC; Ca2+; Orai1; PP2A; voltage gated Ca2+ channels
• Accesso online: DOAB: download the publication; DOAB: description of the publication

Ca2+ is a key second messenger in the intricate workings of the heart. In cardiac myocytes, Ca2+ signaling controls or modulates electrophysiological function, excitation-contraction coupling, contractile function, energy balance, cell death, and gene transcription. Thus, diverse Ca2+-dependent regu...