Cancer Metabolomics 2018
The metabolomics approach, defined as the study of all endogenously-produced low-molecular-weight compounds, appeared as a promising strategy to define new cancer biomarkers. Information obtained from metabolomic data can help to highlight disrupted cellular pathways and, consequently, contribute to...
Saved in:
Main Author: | |
---|---|
Other Authors: | , |
Format: | Electronic Book Chapter |
Language: | English |
Published: |
MDPI - Multidisciplinary Digital Publishing Institute
2019
|
Subjects: | |
Online Access: | DOAB: download the publication DOAB: description of the publication |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
MARC
LEADER | 00000naaaa2200000uu 4500 | ||
---|---|---|---|
001 | doab_20_500_12854_42643 | ||
005 | 20210211 | ||
003 | oapen | ||
006 | m o d | ||
007 | cr|mn|---annan | ||
008 | 20210211s2019 xx |||||o ||| 0|eng d | ||
020 | |a books978-3-03921-346-7 | ||
020 | |a 9783039213450 | ||
020 | |a 9783039213467 | ||
040 | |a oapen |c oapen | ||
024 | 7 | |a 10.3390/books978-3-03921-346-7 |c doi | |
041 | 0 | |a eng | |
042 | |a dc | ||
072 | 7 | |a PS |2 bicssc | |
100 | 1 | |a Pinto, Joana |4 auth | |
700 | 1 | |a Carvalho, Márcia |4 auth | |
700 | 1 | |a De Pinho, Paula Guedes |4 auth | |
245 | 1 | 0 | |a Cancer Metabolomics 2018 |
260 | |b MDPI - Multidisciplinary Digital Publishing Institute |c 2019 | ||
300 | |a 1 electronic resource (184 p.) | ||
336 | |a text |b txt |2 rdacontent | ||
337 | |a computer |b c |2 rdamedia | ||
338 | |a online resource |b cr |2 rdacarrier | ||
506 | 0 | |a Open Access |2 star |f Unrestricted online access | |
520 | |a The metabolomics approach, defined as the study of all endogenously-produced low-molecular-weight compounds, appeared as a promising strategy to define new cancer biomarkers. Information obtained from metabolomic data can help to highlight disrupted cellular pathways and, consequently, contribute to the development of new-targeted therapies and the optimization of therapeutics. Therefore, metabolomic research may be more clinically translatable than other omics approaches, since metabolites are closely related to the phenotype and the metabolome is sensitive to many factors. Metabolomics seems promising to identify key metabolic pathways characterizing features of pathological and physiological states. Thus, knowing that tumor metabolism markedly differs from the metabolism of normal cells, the use of metabolomics is ideally suited for biomarker research. Some works have already focused on the application of metabolomic approaches to different cancers, namely lung, breast and liver, using urine, exhaled breath and blood. In this Special Issue we contribute to a more complete understanding of cancer disease using metabolomics approaches. | ||
540 | |a Creative Commons |f https://creativecommons.org/licenses/by-nc-nd/4.0/ |2 cc |4 https://creativecommons.org/licenses/by-nc-nd/4.0/ | ||
546 | |a English | ||
650 | 7 | |a Biology, life sciences |2 bicssc | |
653 | |a cell transporters | ||
653 | |a pharmacodynamics | ||
653 | |a cell growth | ||
653 | |a in vitro study | ||
653 | |a metabolomic signatures | ||
653 | |a endometabolome | ||
653 | |a lung cancer | ||
653 | |a metabolomics | ||
653 | |a chemometric methods | ||
653 | |a bladder cancer | ||
653 | |a mTOR | ||
653 | |a metabolite profiling | ||
653 | |a metabolic pathways | ||
653 | |a hepatocellular carcinoma | ||
653 | |a glutamate | ||
653 | |a senescence MCF7 | ||
653 | |a breath analysis | ||
653 | |a bio actives | ||
653 | |a biomarker | ||
653 | |a gas chromatography-mass spectrometry (GC-MS) | ||
653 | |a GC-MS | ||
653 | |a lung | ||
653 | |a omics | ||
653 | |a nutraceuticals | ||
653 | |a glutaminase | ||
653 | |a metabolism | ||
653 | |a acylcarnitines | ||
653 | |a Erwinaze | ||
653 | |a Kidrolase | ||
653 | |a glutathione | ||
653 | |a targeted metabolomics | ||
653 | |a apoptosis | ||
653 | |a SLC1A5 | ||
653 | |a essential amino acids | ||
653 | |a cancer progression | ||
653 | |a ASCT2 | ||
653 | |a HR MAS | ||
653 | |a alanine | ||
653 | |a analytical platforms | ||
653 | |a volatile organic compound | ||
653 | |a glutaminolysis | ||
653 | |a isotope tracing analysis | ||
653 | |a asparaginase | ||
653 | |a vitamin E | ||
653 | |a breast cancer | ||
653 | |a prognosis | ||
653 | |a early diagnosis | ||
653 | |a tocotrienols | ||
653 | |a NMR | ||
653 | |a prostate cancer | ||
653 | |a in vitro | ||
653 | |a cancer | ||
653 | |a MDA-MB-231 | ||
856 | 4 | 0 | |a www.oapen.org |u https://mdpi.com/books/pdfview/book/1538 |7 0 |z DOAB: download the publication |
856 | 4 | 0 | |a www.oapen.org |u https://directory.doabooks.org/handle/20.500.12854/42643 |7 0 |z DOAB: description of the publication |