Carbohydrates: The yet to be tasted sweet spot of immunity

• Main Author: Deirdre R. Coombe (auth)
• Other Authors: Christopher R. Parish (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2015
• Series: Frontiers Research Topics
• Subjects: Medicine; Heparan sulfate; Siglec; HIV; sialic acid; hyaluronan; galectin; Heparanase; Inflammation; glycosaminoglycan; Glycan
• Online Access: DOAB: download the publication; DOAB: description of the publication

Carbohydrates are extremely abundant bio-molecules; they are on all mammalian cell surfaces as well as on bacterial cell surfaces. In mammals most secreted proteins are glycosylated, with the glycan component comprising a significant amount by mass of the glycoprotein. Although, many years ago carbo...