Cardiac Remodeling: New Insights in Physiological and Pathological Adaptations

The effective management of Cardiac remodeling(CR), remains a major challenge. Heart failure remains the leading cause of death in industrialized countries. Yet, despite the enormity of the problem, effective therapeutic interventions remain elusive. In fact, several initially promising agents were...

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1. autor: Leonardo Roever (auth)
Kolejni autorzy: Antonio C. Palandri Chagas (auth)
Format: Elektroniczne Rozdział
Język:angielski
Wydane: Frontiers Media SA 2017
Seria:Frontiers Research Topics
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Dostęp online:DOAB: download the publication
DOAB: description of the publication
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520 |a The effective management of Cardiac remodeling(CR), remains a major challenge. Heart failure remains the leading cause of death in industrialized countries. Yet, despite the enormity of the problem, effective therapeutic interventions remain elusive. In fact, several initially promising agents were found to decrease mortality in patients recovering from myocardial infarction. Cardiac remodeling is defined as molecular and interstitial changes, manifested clinically by changes in size, mass , geometry and function of the heart in response to certain aggression. Initially, ventricular remodeling aims to maintain stable cardiac function in situations of aggression. 
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653 |a Fibrosis 
653 |a Heart Failure 
653 |a Physiology 
653 |a Inflammation 
653 |a Cardiac Remodeling 
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