Cell-Free Nucleic Acids

• Main Author: Nagy, Bálint (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: MDPI - Multidisciplinary Digital Publishing Institute 2020
• Subjects: Medicine; n/a; screening; single nucleotide polymorphism; predictive and preventive approach; PTEN; cell-free DNAs; fetal fraction; gestational hypertension; RASSF1; CDH1; RT-PCR; cfDNA; statistical models; hematopoietic stem cell transplantation; NanoString; solid organ transplantation; copy number variants; sarcomas; liquid biopsy; obesity; fetal DNA; neutrophil extracellular traps; mammography; non-invasive prenatal testing; ovarian cancer; circulating miRNA; pyrosequencing; growth retardation; preeclampsia; gestational diabetes mellitus; biomarker; inflammatory bowel disease; multi-level diagnostics; PAX1; population study; nuclease activity; NETosis; omics; piRNA; cell-free DNA; prediction; leiomyosarcomas; network analysis; NGS; statistical methods; circulating nucleic acids; deletion/insertion polymorphism; gender differences; leiomyomas; fetal growth restriction; blood plasma; exosomes; miRNA; pregnancy-related complications; NIPT; genetic marker; cell-free nucleic acids; extracellular vesicles; expression; next generation sequencing; breast cancer; individualized patient profile; circulating tumor cells; maternal serum screening; personalized medicine; embryo culture medium; C19MC microRNA; DNA; cell-free RNAs; z-score; fetal cells; microchimerism; aging; plasma
• Online Access: DOAB: download the publication; DOAB: description of the publication

The deficits of mammography and the potential of noninvasive diagnostic testing using circulating miRNA profiles are presented in our first review article. Exosomes are important in the transfer of genetic information. The current knowledge on exosome-associated DNAs and on vesicle-associated DNAs a...