Central Nervous System Metastases in Lung Cancer Patients: From Prevention to Diagnosis and Treatment

• Main Author: Deepa S. Subramaniam (auth)
• Other Authors: Lizza E.L. Hendriks (auth), Anne-Marie C. Dingemans (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2019
• Series: Frontiers Research Topics
• Subjects: Medicine; lung cancer; driver mutations; treatment; brain metastases; leptomeningeal metastases; cranial radiation; prediction; diagnosis
• Online Access: DOAB: download the publication; DOAB: description of the publication

Approximately 40% of lung cancer patients will develop central nervous system (CNS) metastases during the course of their disease. Most of these are brain metastases, but up to 10% will develop leptomeningeal metastases. Known risk factors for CNS metastases development are small cell lung cancer (S...