Cerebral endothelial and glial cells are more than bricks in the Great Wall of the brain: Insights into the way the blood-brain barrier actually works (Celebrating the centenary of Goldman's experiments)

• Main Author: George E. Barreto (auth)
• Other Authors: Rubem C A Guedes (auth), Jose A G Agundez (auth), Ramon Santos El Bacha (auth), Elena Garcia Martin (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2015
• Series: Frontiers Research Topics
• Subjects: Neurosciences; glial cells; Stroke; Cerebral endothelial cells; BBB; Oxidative Stress; Glioma; Blood Brain Barrier; xenobiotic metabolizing enzymes; Parkinsons disease; Neuroinflammation
• Online Access: DOAB: download the publication; DOAB: description of the publication

When Ehrlich discovered the first evidence of the blood-brain barrier in 1885, he probably did not perceive the Great Wall that remained hidden from consciousness inside the central nervous system. Ehrlich had observed that acidic vital dyes did not stain the brain if they were injected into the blo...