Circulating Tumor Cells: Finding Rare Events for A Huge Knowledge of Cancer Dissemination

• Hoofdauteur: Alix-Panabieres, Catherine (auth)
• Formaat: Elektronisch Hoofdstuk
• Taal: Engels
• Gepubliceerd in: MDPI - Multidisciplinary Digital Publishing Institute 2020
• Onderwerpen: Medicine; n/a; FOLFIRINOX; immunofluorescence imaging; AR-V7; circulating tumour cells; chemoradioresistance; CTC-based treatment decisions; rVAR2; immunophenotyping; immune system; CellSearch®; flow cytometry; clinical trials; circulating tumor DNA; synaptophysin; stem cells; colorectal cancer; melanoma; CTC biology; platelets; AR; CTC capture technology; castration resistant prostate cancer (CRPC); PD-L1 expression; rovalpituzumab tesirine; HMB-45; thymidylate synthase; ctDNA; tumor cell dissemination; solid cancers; metastasis; locally advanced rectal cancer; miRNA; epithelial-to-mesenchymal transition (EMT); NSCLC; tumor biomarkers; tumor stem cells; circulating tumor cells; major histocompatibility complex class I (MHCI); bone marrow; heterogeneity; cerebrospinal liquid biopsy; fish; glioma; in vivo flow cytometry; colorectal surgery; CellSearch; single-cell analysis; disseminated tumor cells; EasyCount slides; microsatellite instability; circulating plasma cells; circulating leukemia cells; ARV7; SLUG; androgen receptor; metastatic colorectal cancer; leukocyte-derived extracellular vesicles; prostate cancer (PCa); neutrophils; liquid biopsy; enzalutamide; CD133; enrichment and detection technologies; biomarkers; immune checkpoint inhibitors; biomarker; RAD23B; microbiome; integrin B1; ACCEPT; emboli; small-cell lung carcinoma; EPISPOT; microfluidics; early breast cancer; circulating tumor cells (CTC); tumor-initiating cells (TICs); immunomodulation; xenograft models; CTC-derived xenografts; malaria; circulating tumor cells (CTCs); clinical utility; exosomes; liquid surgery; ctRNA; CTCs; epithelial-mesenchymal transition; targeted therapy; hematological cells; gene expression analysis; hepatocellular carcinoma (HCC); breast cancer; EpCAM enrichment; prostate cancer; CTC; abiraterone; fibronectin; CTC-derived ex vivo models; CTMat; chromogranin A; CTM; exosome
• Online toegang: DOAB: download the publication; DOAB: description of the publication

The analysis of circulating tumor cells (CTCs) as a real-time liquid biopsy approach can be used to obtain new insights into metastasis biology, and as companion diagnostics to improve the stratification of therapies and to obtain insights into the therapy-induced selection of cancer cells. In this...