Computational and Experimental Approaches in Multi-Target Pharmacology

• मुख्य लेखक: Thomas J. Anastasio (auth)
• स्वरूप: इलेक्ट्रोनिक पुस्तक अध्याय
• भाषा: अंग्रेज़ी
• प्रकाशित: Frontiers Media SA 2017
• श्रृंखला: Frontiers Research Topics
• विषय: Pharmacology; systems biology; computer modeling; drug repurposing; synergy; drug discovery; drug combination; high throughput screening; multidrug therapeutics; polypharmacy; multifactorial process
• ऑनलाइन पहुंच: DOAB: download the publication; DOAB: description of the publication

सारांश

The next frontier in pharmacology is the development of multi-target strategies in which pathological processes are controlled by pharmacologically manipulating them at many different points at once. Designing multi-target strategies will require deep understanding of the complex physiology that underlies pathological processes. It will also require the development of single drugs with multiple targets, or combinations of drugs with compatible pharmacokinetics that work synergistically to maximize desirable effects while minimizing unwanted side effects. This e-Book contains ten original articles, each addressing a different aspect of this challenge. Together they open new perspectives and show the way forward in the development of multi-target therapeutics.

भौतिक वर्णन

1 electronic resource (122 p.)

आईएसबीएन

978-2-88945-252-1
9782889452521

अभिगमन

Open Access