Current Progress and Challenges in the Development of a Hepatitis C Virus Vaccine

• Hoofdauteur: Thomas F. Baumert (auth)
• Andere auteurs: Steven K.H. Foung (auth)
• Formaat: Elektronisch Hoofdstuk
• Taal: Engels
• Gepubliceerd in: Frontiers Media SA 2019
• Reeks: Frontiers Research Topics
• Onderwerpen: Medicine; Conformational epitopes; humoral immunity; Conformational structures; neutralizing antibodies; Vaccine; Hepatitis C virus; hypervariability and flexibility
• Online toegang: DOAB: download the publication; DOAB: description of the publication

More than 70 million people worldwide are infected with hepatitis C virus, a major cause of liver cirrhosis, liver failure and hepatocellular carcinoma world-wide. In the last decade, this cancer has emerged as the second leading cause of cancer death and the global burden is increasing by two milli...