DNA helicases: expression, functions and clinical implications

• Main Author: Fumiaki Uchiumi (auth)
• Other Authors: Masayuki Seki (auth), Yasuhiro Furuichi (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2015
• Series: Frontiers Research Topics
• Subjects: Genetics (non-medical); DNA Repair; Aging; helicases; Telomere; Cancer
• Online Access: DOAB: download the publication; DOAB: description of the publication

Helicases are the proteins that bind to double- or single-stranded DNA and/or RNA chains to unwind higher order structures, usually consuming energy from the hydrolysis of ATP molecules. The biological roles of helicases are associated with a variety of DNA and/or RNA metabolisms, including DNA-repl...