DNA helicases: expression, functions and clinical implications

• मुख्य लेखक: Fumiaki Uchiumi (auth)
• अन्य लेखक: Masayuki Seki (auth), Yasuhiro Furuichi (auth)
• स्वरूप: इलेक्ट्रोनिक पुस्तक अध्याय
• भाषा: अंग्रेज़ी
• प्रकाशित: Frontiers Media SA 2015
• श्रृंखला: Frontiers Research Topics
• विषय: Genetics (non-medical); DNA Repair; Aging; helicases; Telomere; Cancer
• ऑनलाइन पहुंच: DOAB: download the publication; DOAB: description of the publication

Helicases are the proteins that bind to double- or single-stranded DNA and/or RNA chains to unwind higher order structures, usually consuming energy from the hydrolysis of ATP molecules. The biological roles of helicases are associated with a variety of DNA and/or RNA metabolisms, including DNA-repl...