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DNA Replication Controls

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The conditions for DNA replication are not ideal, owing to endogenous and exogenous replication stresses that lead to arrest of the replication fork. Arrested forks are among the most serious threats to genomic integrity because they can break or rearrange, leading to genomic instability, which is a...

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Bibliográfalaš dieđut
Váldodahkki: Eishi Noguchi (Ed.) (auth)
Materiálatiipa: Elektrovnnalaš Girjji oassi
Giella:eaŋgalasgiella
Almmustuhtton: MDPI - Multidisciplinary Digital Publishing Institute 2017
Fáttát:
Biology, life sciences
DNA helicase
DNA replication
replication stress
replication checkpoint
DNA polymerase
telomere replication
cancer
genomic instability
DNA repair
replisome
translesion synthesis
Liŋkkat:DOAB: download the publication
DOAB: description of the publication
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Govvádus
Čoahkkáigeassu:The conditions for DNA replication are not ideal, owing to endogenous and exogenous replication stresses that lead to arrest of the replication fork. Arrested forks are among the most serious threats to genomic integrity because they can break or rearrange, leading to genomic instability, which is a hallmark of cancers and aging-related disorders.
Olgguldas hápmi:1 electronic resource (X, 304 p.)
ISBN:books978-3-03842-569-4
9783038425694
9783038425687
Beassan:Open Access

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