DNA Replication Controls
The conditions for DNA replication are not ideal, owing to endogenous and exogenous replication stresses that lead to arrest of the replication fork. Arrested forks are among the most serious threats to genomic integrity because they can break or rearrange, leading to genomic instability, which is a...
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| Main Author: | |
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| Format: | Electronic Book Chapter |
| Language: | English |
| Published: |
MDPI - Multidisciplinary Digital Publishing Institute
2017
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| Subjects: | |
| Online Access: | DOAB: download the publication DOAB: description of the publication |
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| 100 | 1 | |a Eishi Noguchi (Ed.) |4 auth | |
| 245 | 1 | 0 | |a DNA Replication Controls |
| 260 | |b MDPI - Multidisciplinary Digital Publishing Institute |c 2017 | ||
| 300 | |a 1 electronic resource (X, 304 p.) | ||
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| 506 | 0 | |a Open Access |2 star |f Unrestricted online access | |
| 520 | |a The conditions for DNA replication are not ideal, owing to endogenous and exogenous replication stresses that lead to arrest of the replication fork. Arrested forks are among the most serious threats to genomic integrity because they can break or rearrange, leading to genomic instability, which is a hallmark of cancers and aging-related disorders. | ||
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| 546 | |a English | ||
| 650 | 7 | |a Biology, life sciences |2 bicssc | |
| 653 | |a DNA helicase | ||
| 653 | |a DNA replication | ||
| 653 | |a replication stress | ||
| 653 | |a replication checkpoint | ||
| 653 | |a DNA polymerase | ||
| 653 | |a telomere replication | ||
| 653 | |a cancer | ||
| 653 | |a genomic instability | ||
| 653 | |a DNA repair | ||
| 653 | |a replisome | ||
| 653 | |a translesion synthesis | ||
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| 856 | 4 | 0 | |a www.oapen.org |u https://directory.doabooks.org/handle/20.500.12854/45329 |7 0 |z DOAB: description of the publication |