Effects of Mycotoxins on the Intestine

• Main Author: Oswald, Isabelle P. (auth)
• Other Authors: Pinton, Philippe (auth), Alassane-Kpembi, Imourana (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: MDPI - Multidisciplinary Digital Publishing Institute 2019
• Subjects: Medicine; toxicity; intestinal epithelial cells; n/a; piglets; toll-like receptors; permeability; aflatoxin M1; pig; N-acetylcysteine; pigs; histology; pre-pubertal gilts; histopathological lesions; Mitochondrial apoptosis; explant technique; Lactobacillus; liver; ergot alkaloids; digestive tract; ultrastructure; hydrogen-rich water; genotoxicity; proliferating cell nuclear antigen; mycotoxin; feed; intestinal morphology; functional oligosaccharides; Saccharomyces cerevisiae boulardii CNCM I-1079; jejunum; small intestine; detoxification; vasoactive intestinal polypeptide; PCR; atlantic salmon; ileum; microbiota; sclerotia; zearalenone; intestine; doses; mycotoxins; transcriptome; lipid metabolism; Zearalenone; caecal water; mice; deoxynivalenol; aflatoxin B1; goblet cells; inflammation; intestinal bacterial flora; SIEC02 cells; piglet; colon microbiota; tight junctions; tight junction; suppressor of cytokine signaling; ochratoxin A; Claviceps; T-2 toxin; MiSeq 16S rDNA sequencing; lactulose; Clostridium sp. WJ06; swine; intestinal microbiota; fumonisin; response; contaminated feed; Fusarium mycotoxins; microbial diversity; enteric nervous system; large intestine; ultrastructural changes; oxidative stress
• Online Access: DOAB: download the publication; DOAB: description of the publication

Mycotoxins are secondary metabolites produced by several fungal species. They can contaminate human food and animal feed, and have been a threat for thousands of years. The gastrointestinal tract is the first target when ingesting mycotoxin-contaminated food or feed. As unlikely as it sounds, the in...