Entwicklung eines mikrofluidischen Zweikammer-Chipsystems mit integrierter Sensorik für die Anwendung in der Tumorforschung

We have developed a microfluidic two-layered channel system based on polycarbonate to investigate the transmigration of cancer cells under flow conditions and defined shear rate using live cell microscopy. The two layers are separated by a porous membrane with an endothelial monolayer on top of the...

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Bibliographic Details
Main Author: Rajabi, Taleieh (auth)
Format: Electronic Book Chapter
Published: KIT Scientific Publishing 2014
Series:Schriften des Instituts für Mikrostrukturtechnik am Karlsruher Institut für Technologie / Hrsg.: Institut für Mikrostrukturtechnik
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Online Access:DOAB: download the publication
DOAB: description of the publication
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245 1 0 |a Entwicklung eines mikrofluidischen Zweikammer-Chipsystems mit integrierter Sensorik für die Anwendung in der Tumorforschung 
260 |b KIT Scientific Publishing  |c 2014 
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520 |a We have developed a microfluidic two-layered channel system based on polycarbonate to investigate the transmigration of cancer cells under flow conditions and defined shear rate using live cell microscopy. The two layers are separated by a porous membrane with an endothelial monolayer on top of the membrane to mimic the blood vessel wall. To extend the measuring capabilities of our microfluidic chip, gold electrodes were structured on the membrane using optical lithography and chemical etching. 
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546 |a German 
650 7 |a Technology: general issues  |2 bicssc 
653 |a membrane 
653 |a Krebszellen 
653 |a SensorikCancer cell 
653 |a Metastasierung 
653 |a Mikrofluidik 
653 |a Blutgefäß 
653 |a sensors 
653 |a Membran 
653 |a Blood vessel 
653 |a Impedanz 
653 |a microfluidic 
653 |a Impedance 
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