Epigenetic pathways in PTSD: How traumatic experiences leave their signature on the genome
This research topic focuses on epigenetic components of PTSD. Epigenetic mechanisms are a class of molecular mechanisms by which environmental influences, including stress, can interact with the genome to have long-term consequences for brain plasticity and behavior. Articles herein include empirica...
Kaydedildi:
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| Diğer Yazarlar: | , |
| Materyal Türü: | Elektronik Kitap Bölümü |
| Dil: | İngilizce |
| Baskı/Yayın Bilgisi: |
Frontiers Media SA
2015
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| Seri Bilgileri: | Frontiers Research Topics
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| Konular: | |
| Online Erişim: | DOAB: download the publication DOAB: description of the publication |
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| Özet: | This research topic focuses on epigenetic components of PTSD. Epigenetic mechanisms are a class of molecular mechanisms by which environmental influences, including stress, can interact with the genome to have long-term consequences for brain plasticity and behavior. Articles herein include empirical reports and reviews that link stress and trauma with epigenetic alterations in humans and animal models of early- or later-life stress. Themes present throughout the collection include: DNA methylation is a useful biomarker of stress and treatment outcome in humans; epigenetic programming of stress-sensitive physiological systems early in development confers an enhanced risk on disease development upon re-exposure to trauma or stress; and, long-lived fear memories are associated with epigenetic alterations in fear memory and extinction brain circuitry. |
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| Fiziksel Özellikler: | 1 electronic resource (158 p.) |
| ISBN: | 978-2-88919-458-2 9782889194582 |
| Erişim: | Open Access |