Epigenetic pathways in PTSD: How traumatic experiences leave their signature on the genome
This research topic focuses on epigenetic components of PTSD. Epigenetic mechanisms are a class of molecular mechanisms by which environmental influences, including stress, can interact with the genome to have long-term consequences for brain plasticity and behavior. Articles herein include empirica...
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| Format: | Electronic Book Chapter |
| Language: | English |
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Frontiers Media SA
2015
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| Series: | Frontiers Research Topics
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| Subjects: | |
| Online Access: | DOAB: download the publication DOAB: description of the publication |
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| 100 | 1 | |a Tania L. Roth |4 auth | |
| 700 | 1 | |a Karestan C. Koenen |4 auth | |
| 700 | 1 | |a David M. Diamond |4 auth | |
| 245 | 1 | 0 | |a Epigenetic pathways in PTSD: How traumatic experiences leave their signature on the genome |
| 260 | |b Frontiers Media SA |c 2015 | ||
| 300 | |a 1 electronic resource (158 p.) | ||
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| 490 | 1 | |a Frontiers Research Topics | |
| 506 | 0 | |a Open Access |2 star |f Unrestricted online access | |
| 520 | |a This research topic focuses on epigenetic components of PTSD. Epigenetic mechanisms are a class of molecular mechanisms by which environmental influences, including stress, can interact with the genome to have long-term consequences for brain plasticity and behavior. Articles herein include empirical reports and reviews that link stress and trauma with epigenetic alterations in humans and animal models of early- or later-life stress. Themes present throughout the collection include: DNA methylation is a useful biomarker of stress and treatment outcome in humans; epigenetic programming of stress-sensitive physiological systems early in development confers an enhanced risk on disease development upon re-exposure to trauma or stress; and, long-lived fear memories are associated with epigenetic alterations in fear memory and extinction brain circuitry. | ||
| 540 | |a Creative Commons |f https://creativecommons.org/licenses/by/4.0/ |2 cc |4 https://creativecommons.org/licenses/by/4.0/ | ||
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| 650 | 7 | |a Medicine |2 bicssc | |
| 653 | |a PTSD | ||
| 653 | |a stress | ||
| 653 | |a Fear | ||
| 653 | |a DNA Methylation | ||
| 653 | |a Histones | ||
| 653 | |a miRNA | ||
| 856 | 4 | 0 | |a www.oapen.org |u http://journal.frontiersin.org/researchtopic/966/epigenetic-pathways-in-ptsd-how-traumatic-experiences-leave-their-signature-on-the-genome |7 0 |z DOAB: download the publication |
| 856 | 4 | 0 | |a www.oapen.org |u https://directory.doabooks.org/handle/20.500.12854/46667 |7 0 |z DOAB: description of the publication |