Epigenetics of B Cells and Antibody Responses

• Main Author: Paolo Casali (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2016
• Series: Frontiers Research Topics
• Subjects: Medicine; BLIMP-1; CSR; immunoglobulin; memory B cell; Plasma cell; V(D)J Recombination; microRNA; SHM; AID; epigenetics
• Online Access: DOAB: download the publication; DOAB: description of the publication

Epigenetics is the study of changes in gene activity that are heritable but not caused by changes in the DNA sequence. By modulating gene activities, epigenetic changes regulate cell functions. They include DNA methylation, histone posttranslational modifications and gene silencing by the action of...