Evolution, Composition and Regulation of Supernumerary B Chromosomes

• Main Author: Martins, Cesar (auth)
• Other Authors: Trifonov, Vladimir (auth), Houben, Andreas (auth), Jones, Neil (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: MDPI - Multidisciplinary Digital Publishing Institute 2019
• Subjects: Biology, life sciences; parent-of-origin effects; fluorescent in situ hybridization; coverage ratio analysis; n/a; ribosomal DNA; reactivation; cytogenetics; epigenetics; heterochromatin; interphase nucleus; whole genome resequencing; transmission; grasshoppers; genome instability; dot-like (micro) Bs; ?s; B chromosome; supernumerary elements; transcription of heterochromatin; maternal X chromosome; supernumerary chromosome; population analysis; supernumerary; repeat clusters; extra chromosomes; genes; tandem repeats; B morphotypes; repetitive DNA; repetitive elements; DNA copy number variation; chromosome polymorphism; satellite DNA; mammals; maize B chromosome; additional chromosomes; inactivation; drive; B chromosomes; FISH (fluorescence in situ hybridisation); organelle DNA; Orthoptera; origin; supernumerary chromosomes; karyotype evolution; GISH (genomic in situ hybridisation); DNA composition; de novo centromere formation; genomics; paternal X chromosome; euchromatin degradation; supernumerary chromosomal segments (SCS) evolution; centromere; sSMC; Prospero autumnale complex; next-generation sequencing; Drosophila; host/parasite interaction; Apodemus peninsulae; genome evolution; evolution; teleost; chromosome evolution; microdissected DNA probes; controlling element; mobile element; RNA-Seq; karyotypes; karyotypic characteristics; RepeatExplorer
• Online Access: DOAB: download the publication; DOAB: description of the publication

Supernumerary B chromosomes (Bs) are dispensable genetic elements found in thousands of species of plants and animals, and some fungi. Since their discovery more than a century ago, they have been a source of puzzlement, as they only occur in some members of a population and are absent from others. When they do occur, they are often harmful, and in the absence of "selfishness", based on mechanisms of mitotic and meiotic drive, there appears to be no obvious reason for their existence. Cytogeneticists have long wrestled with questions about the biological existence of these enigmatic elements, including their lack of any adaptive properties, apparent absence of functional genes, their origin, sequence organization, and co-evolution as nuclear parasites. Emerging new technologies are now enabling researchers to step up a gear, to look enthusiastically beyond the previous limits of the horizon, and to uncover the secrets of these "silent" chromosomes. This book provides a comprehensive guide to theoretical advancements in the field of B chromosome research in both animal and plant systems.