Extraintestinal Manifestations of Coeliac Disease

• Main Author: Sanders, David (auth)
• Other Authors: Hadjivassiliou, Marios (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: MDPI - Multidisciplinary Digital Publishing Institute 2019
• Subjects: Biology, life sciences; gluten; Gluten ataxia; gluten sensitive enteropathy; extraintestinal; atopic dermatitis; eating disorders; antigliadin antibodies; ganglioside; fracture; polyglandular autoimmune syndrome; potential celiac disease; B cell; molecular mimicry; fatigue; non-coeliac gluten sensitivity (NCGS); alopecia areata; fractures; energy; autoimmune pancreatitis; coeliac disease; villous atrophy; autoimmunity; psoriasis; male; ADHD; non-alcoholic fatty liver disease; autoantibody; motor and vocal/phonic tics; mild enteropathy; natural history; gliadin; prevalence; long-term prognosis; extra-intestinal; non-celiac gluten sensitivity; celiac disease; antigliadin antibody titre; transglutaminase; migraine; rosacea; celiac trait; anxiety disorders; prognosis; cutaneous vasculitis; one-year adherence; incidence; dermatitis herpetiformis; screening; gluten free diet; recognition; children and adults; gluten neuropathy; psychosis; obsessive-compulsive disorder (OCD); liver immunity; intermolecular help; recurrent aphtous ulceration; tolerance; glandular autoimmunity; gastrointestinal symptoms; MR spectroscopy; gluten-free diet; bone health; diagnosis; early developing celiac disease; genetic gluten intolerance; osteoporosis; biomarker; gastrointestinal; clinical presentation; latent celiac disease; synapsin; extra-intestinal manifestations; quality of life; gluten ataxia; Gilles de la Tourette syndrome (GTS); intestinal barrier; celiac hepatitis; small bowel; gut-liver axis; autoimmune thyroid disease; type 1 diabetes; T cell; epidermal transglutaminase; autism; pancreatic disorders; gluten sensitivity; urticaria; depression; movement disorders; headache; psychiatric disorders
• Online Access: DOAB: download the publication; DOAB: description of the publication

Coeliac Disease (CD) affects at least 1% of the population. “Classical” CD refers to gastrointestinal presentations with anaemia and gastrointestinal symptoms. CD can, however, present with extraintestinal manifestations, the commonest of which are dermatitis herpetiformis and neurological presentations (e.g., ataxia, neuropathy, encephalopathy). Recognition and research into the pathophysiology of such manifestations is likely to enhance our understanding of this complex autoimmune disorder.