Genome Mining and Marine Microbial Natural Products

• 1. Verfasser: Hong, Kui (auth)
• Weitere Verfasser: Zhang, Changsheng (auth), Dobson, Alan (auth)
• Format: Elektronisch Buchkapitel
• Sprache: Englisch
• Veröffentlicht: MDPI - Multidisciplinary Digital Publishing Institute 2020
• Schlagworte: Biology, life sciences; antibacterial activity; polyketide synthase; halo-extremophyles; antibacterial; gene cluster; Penicillium chrysogenum; bacillomycin; secondary metabolites; drug discovery; biosynthesis; polycyclic tetramate macrolactams; actinobacteria; biosynthetic gene clusters; phylotype; comparative genomics; IclR family regulator; polyketide antibiotics; antifungal; fatty acid amide; Antarctica; marine microorganisms; NdgRyo; nonribosomal peptides; Marisediminicola; genome mining; antimicrobial; sponge; Stachybotrys; carotenoid; marine; archaea; haloenzymes; natural products; Streptomyces sp. SCSIO 40010; 16S rRNA metagenomics; ecotype; medicinal chemistry; cytotoxicity; marine natural products (MNPs); Streptomyces; marine Bacillus; antimicrobial activity; amino compound; bacillibactin; meroterpenoid; fibrinolytic activity; metal stress technique; isoindolinone biosynthesis; Streptomyces pratensis; histone-deacetylase inhibitor; marine natural product; Odiel marshlands
• Online-Zugang: DOAB: download the publication; DOAB: description of the publication

Two review papers, eight research articles, and one brief report were published in this Special Issue. They showed the rich resources that are present within the genomes of marine microorganisms and discussed the use of recently developed tools and technologies to exploit this genetic richness. Exam...