Histamine H4 receptor. A Novel Drug Target For Immunoregulation and Inflammation

• Hoofdauteur: Stark, Holger (auth)
• Formaat: Elektronisch Hoofdstuk
• Taal: Engels
• Gepubliceerd in: De Gruyter 2013
• Onderwerpen: Biochemistry; Allergy; Inflammation; Pruritus; Asthma; Drug Target; Biogenic Amin; G protein coupled receptors; H4R ligands; Drug Development; Clinical Candidates; Autoimmune Disorders; Cancer
• Online toegang: DOAB: download the publication; DOAB: description of the publication

H4R is the newest member of the histamine receptor family, which was discovered about twelve years ago. It is considered a very promising drug target. The effort to improve the pharmacokinetic properties of the currently available H4R ligands is reflected in a steadily growing number of scientific p...