Homeostatic and retrograde signaling mechanisms modulating presynaptic function and plasticity

• Main Author: Michael A. Sutton (auth)
• Other Authors: Dion Dickman (auth), Jaichandar Subramanian (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2016
• Series: Frontiers Research Topics
• Subjects: Neurosciences; homeostatic plasticity; retrograde signaling; Neurological Disease; Presynaptic adaptation; neurotransmitter release
• Online Access: DOAB: download the publication; DOAB: description of the publication

Activity within neural circuits shapes the synaptic properties of component neurons in a manner that maintains stable excitatory drive, a process referred to as homeostatic plasticity. These potent and adaptive mechanisms have been demonstrated to modulate activity at the level of an individual neur...